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3

Apr, 2015

Topact Gel

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Composition: Topact gel contains Ketoprofen B.P 2.5%w/w Pharmacological Properties Pharmacodynamics It belongs to a class of medicines known as Non-steroidal Anti-inflammatory Drugs (NSAIDs) for topical use. It has anti-inflammatory and analgesic actions.Pharmacokinetics: By cutaneous route, absorption is very low. In fact, the percutaneous application of 50-150 mg of Ketoprofen produces plasma levels of the active ingredient of 0.08-0.15 μg/mL approximately 5-8 hours after application. Indications: For local relief of pain and inflammation associated with rheumatic and muscular disorders and soft tissue injuries such as acute strains and sprains. Dosage and […]

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3

Apr, 2015

Comax DPS

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Anti-malarial / blood schizonticide. COMPOSITION: Each 5ml when reconstituted contains 15mg Artemether and 90mg Lumefantrine. RECONSTITUTION INSTRUCTIONS: Tap  bottle to disloge powder. Add 42ml of freshly boiled and cooled water. Shake well until all powder is dispersed. DESCRIPTION: Artemether is a sesquiterpene lactone derived from the naturally occurring substance artemisinin. Lumefantrine is a synthetic racemic fluorene mixture. PHARMACODYNAMICS: COMAX DPS comprises a fixed ratio of 1:6 parts of Artemether and Lumefantrine, respectively. The site of anti-parasitic action of both components is the food vacuole of the malaria parasite, where they […]

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16

Mar, 2015

MUCOTHIOL 5% SYRUP

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COMPOSITION: Each 5ml contains 250mg of Carbocisteine. Also contains Methyl Paraben and Propyl Paraben. Clinical Pharmacology Pharmacodynamics: Carbocisteine (S-carboxymethyl L-cysteine) has been shown in normal and bronchitic animal models to affect the nature and amount of mucus glycoprotein which is secreted by the respiratory tract. . Studies in humans have demonstrated that carbocisteine reduces goblet cell hyperplasia. Carbocisteine can therefore be demonstrated to have a role in the management of disorders characterised by abnormal mucus.. Pharmacokinetics: Carbocisteine is rapidly absorbed from the GI tract. Indications: Carbocisteine is a mucolytic agent […]

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16

Mar, 2015

MUCOTHIOL 2% SYRUP

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COMPOSITION: Each 5ml contains 100mg of Carbocisteine. Also contains Methyl Paraben and Propyl Paraben. Clinical Pharmacology Pharmacodynamics: Carbocisteine (S-carboxymethyl L-cysteine) has been shown in normal and bronchitic animal models to affect the nature and amount of mucus glycoprotein which is secreted by the respiratory tract. . Studies in humans have demonstrated that carbocisteine reduces goblet cell hyperplasia. Carbocisteine can therefore be demonstrated to have a role in the management of disorders characterised by abnormal mucus.. Pharmacokinetics: Carbocisteine is rapidly absorbed from the GI tract. Indications: Carbocisteine is a mucolytic agent […]

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25

Feb, 2015

VIRAVAL – 500

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For the use of a registered medical practitioner, a Hospital or laboratory only. COMPOSITION: Each film coated tablet contains: Valacyclovir Hydrochloride U.S.P  equivalent to 500mg Valacyclovir. CLINICAL PHARMACOLOGY: Valacyclovir is a prodrug, an esterified version of acyclovir that has greater oral bioavailability (about 55%) than acyclovir (10-20%). It is converted by esterases to the active drug acyclovir, as well as the amino acid valine, via hepatic first-pass metabolism. Acyclovir is selectively converted into a monophosphate form by viral thymidine kinase, which is far more effective (3000 times) in phosphorylation than […]

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25

Feb, 2015

Silvamax Cream

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Composition Contains Silver Sulfadiazine U.S.P 1% w/w and Chlorhexidine Gluconate solution B.P. equivalent to Chlorhexidine Gluconate 0.2%w/w. Pharmaceutical Form Cream for topical application on human beings. Therapeutic Indications For the treatment of minor burns and scalds, scratches, cuts, and abrasions, sunburns blisters and infected cracked skin. It may also be used as an aid to short term treatment of infection in leg ulcers and pressure sores, and for the prophylaxis of infection in skin graft donor sites and extensive abrasions. Posology and Method of Administration To be applied topically. Cleansing […]

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3

Jan, 2015

MUCOTHIOL WITH PROMETHAZINE SYRUP

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MUCOTHIOL WITH PROMETHAZINE SYRUP : COMPOSITION: Each 5ml contains 100mg of Carbocisteine and 2.5mg of Promethazine Hydrochloride. Clinical Pharmacology Pharmacodynamics: Carbocisteine (S-carboxymethyl L-cysteine) has been shown in normal and bronchitic animal models to affect the nature and amount of mucus glycoprotein which is secreted by the respiratory tract. Studies in humans have demonstrated that carbocisteine reduces goblet cell hyperplasia. Carbocisteine can therefore be demonstrated to have a role in the management of disorders characterised by abnormal mucus. Promethazine  is a potent, long acting, antihistamine with additional anti-emetic central sedative and […]

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3

Jan, 2015

Clith 500

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CLITH-500 Medium and broad spectrum macrolide antibiotic Composition: Each Clith-500 caplet contains 500mg Clarithromycin B.P. Identification: Pale yellow film coated caplet scored on one side, plain on the reverse side. Pharmacology: Clith-500 exerts its antibacterial action by binding to the 50S ribosomal subunits of susceptible bacteria and thereby suppressing protein synthesis. In vitro sensitivity does not necessarily imply in vivo efficacy. The in vitro antibacterial spectrum of pathogens usually sensitive to Clith-500 includes Streptococcus agalactie, Streptococcus pyogenes, Streptococcus pneumonia, Legionella pneumonia, Mycoplasma pneumonia, Chlamydia trachomatis, Branhamella catarrhalis, certain strains of […]

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15

Nov, 2014

Unibrol Leaflet

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Composition: Unibrol syrup: Each 5ml contains 125mg aminosidine  U.S.P  (as sulphate). Unibrol tablet: Each tablet contains 250mg aminosidine  U.S.P  (as sulphate). Clinical pharmacology: Aminosidine is active against various protozoa including: Leishmania spp; Entamoeba histolytica, and Cryptosporidium spp. In addition, it has an antibacterial spectrum similar to that of neomycin. It is active against many strains of gram-negative bacteria including species of Brucella, Calymmatobacterium, Campylobacter, Citrobacter, Escherichia, Enterobacter, Klebsiella, proteus, Serratia Vibrio and Yersinia. Aminosidine has been reported to be active against Mycobacterium tuberculosis but lacks activity against Pseudomonas aeruginosa. Pharmacokinetics: […]

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28

Oct, 2014

THROZA-DRY POWDER SUSPENSION

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For the use of a Registered Medical Practitioner, a Hospital or a Laboratory only Composition: After reconstitution each 5ml contains Azithromycin Dihydrate B.P equivalent to 200mg Azithromycin. DESCRIPTION: Azithromycin is a macrolide antibiotic belonging to the azalide group. The molecule is constructed by adding a nitrogen atom to the lactone ring of erythromycin A. CLINICAL PHARMACOLOGY: The mechanism of action of azithromycin is based upon the suppression of bacterial protein synthesis by binding to the ribosomal 50S sub-unit and inhibition of peptide translocation. PHARMACOKINETICS: The bioavailability of azithromycin after oral […]

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